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Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity

Blood was collected prior to dosing and at predetermined collection times before and after the last dose to assess NAC, cysteine, GSH, catalase, malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) concentrations and reduced-to-oxidized GSH ratio (GSH/GSSG)

First two weeks During the introduction phase, visible results are minimal

2020), showed a significant decrease in NSE in NAC treatment group in stroke patients using Hoffer et al

The DMRs identified were not investigated using IPA software due to decreased quantity